Coenzyme Q10 (CoQ10) or ubiquinone is a substance that helps to convert food into energy. CoQ10 is found in almost every cell in the body and it is a powerful antioxidant. It fights against damaging particles in the body known as free radicals, which damage cell membranes, tamper with DNA and even cause cell death. Scientists believe free radicals contribute to the ageing process, as well as a number of health problems, including heart disease and cancer. Antioxidants, such as CoQ10, can neutralize free radicals and may reduce or even help prevent some of the damage they cause (1).
Its important function is that it acts as a primary scavenger of free radicals (FRs) as it is well located in the membranes in close proximity to the unsaturated lipid chains. It also includes functions like oxidation/reduction control of signal origin and transmission in cells which induce genre expression, control of membrane channels, structure and lipid solubility (2).
Decreased ubiquinone levels have been reported in several diseases including cardiomyopathies, degenerative muscle diseases and hepatocellular carcinomas (3).
CoQ10 is an essential cofactor of enzymes involved in the process that supplies energy (cellular respiration) to all cells, CoQ10 is an intermediate in the electron transport system that generates energy in the form of adenosine triphosphate (ATP); it interferes in the formation of complexes in mitochondrial respiratory chain. Tissues with a high energy requirement, especially the heart and skeletal muscles, contain higher numbers of mitochondria are reliant on maintaining adequate tissue CoQ10 levels for normal functioning (4).
CoQ10 supplements help to reduce swelling in the legs; reduce fluid in the lungs, making breathing easier and increase exercise capacity of heart (1).
CoQ10 has the potential to lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by 10 mm Hg, without significant side effects (1).
Life On CoQ-Life plays a role as a cell membrane protecting antioxidant.
1.Coenzyme 10, umm.edu/health/medical/altmed/supplement/coenzyme-q10
2.Role of coenzyme Q10 as an antioxidant andbioenergizer in periodontal diseases, Indian J Pharmacol. 2010 Dec; 42(6): 334–337.doi: 10.4103/0253-7613.71884
3.Biochemical, physiological and medical aspects of ubiquinone function, Biochimica et Biophysica Acta 1271 (1995) 195-204.
4.Coenzyme Q10 and cardiovascular disease: an overview, October 2015Br J Cardiol 2015;22:160doi:10.5837/bjc.2015.037